Evolutionary transition pathways for changing peptide ligand specificity and structure

Multi-Theory Model for Changing Health Behavior: Evolutionary Process and Strengths and Weak Points

Dear Editor, Generally, in health education and health promotion, theories with characteristics such as the relationship with health behaviors, adequate prognostic power, the existence of empirical evidence of change in behavior, the availability of finite and flexible structures, the ability to change the immediate and long-term behavior at individual, group, and social levels that can be app...

Investigating transition pathways and transition failures and proposing policy solutions to cope with transition failures; Iran’s wind turbine industry

This paper aims to investigate transition paths and reasons of failure of Iran’s wind turbines industry in transition to sustainability successfully. In this regard, a qualitative approach and case study strategy have been used. For this purpose, based on type of national innovation system, the transition path and sustainability transition status of the wind turbines industry in selected countr...

Investigating transition pathways and transition failures and proposing policy solutions to cope with transition failures; Iran’s wind turbine industry

This paper aims to investigate transition paths and reasons of failure of Iran’s wind turbines industry in transition to sustainability successfully. In this regard, a qualitative approach and case study strategy have been used. For this purpose, based on type of national innovation system, the transition path and sustainability transition status of the wind turbines industry in selected countr...

Display Exquisite Ligand Specificity Peptide-MHC Class I Tetrameric Complexes

Solution structure of a beta-peptide ligand for hDM2.

We recently reported a beta-peptide foldamer, beta53-1, that folds into a 14-helix in aqueous solution, binds the oncoprotein hDM2 with submicromolar affinity, and potently inhibits the interaction of hDM2 with a peptide derived from the activation domain of p53 (p53AD). Here, we present the solution structure of beta53-1 in methanol. Details of the structure illustrate fundamental and novel el...